Monthly Archives: September 2020

Our own nanocarriers can also transport drugs

Inside our blood, there are several natural nanocarriers. Lipoproteins are small packages of lipids, stabilised by proteins. These transport lipids and some lipid-soluble vitamins in the blood, and deliver them at the target sites. We have found that some lipid-soluble drugs also  associate with lipoproteins, and a large fraction of these are transported by lipoproteins rather than serum proteins. This new concept of drug transport in the blood means that we have to think differently when estimating pharmacokinetic properties of some drugs. The paper was published in the journal Therapeutic Drug Monitoring.